Invasive skin care

PRF and Biofiller


A new technology was developed using these blood by-products. The plasma is heated to create denatured serum albumin and mixed with natural growth factors from the blood. This in turn creates a biological filler or “BioFiller” derived entirely from whole blood, with enhanced resorption properties that allow the material to last up to 6 months.

Vampire treatment (PRP/PRF)

Your body has the ability to regenerate and treat tissue in all parts of the skin. The stem cells do this every day of your life. PRF stem cell rejuvenation therapy, known as self-rejuvenation therapy, is a leading treatment that harnesses the healing power of platelets and growth factors in your own blood to stimulate the stem cell response.

I-PRF is an abbreviation for the term “platelet-enriched fibrin”. It is the 2nd generation of the old well-known treatment PRP. PRF is known worldwide and has a wide range of indications, including dermatology, cosmetics, dentistry, orthopaedics and other medical branches. It is also known as the Vampire treatment.

I-PRF (Injectable Platelet Rich Fibrin) is a new fibrinogen-rich platelet-containing method for use in liquid form to facilitate the application of substances.

I-PRF is obtained by centrifuging the customer’s blood in the tubes without any additives. The resulting preparation is thus 100% natural and can be safely used in the skin. It represents revolutionary regeneration and skin regeneration process using stem cells and growth factors taken from own blood. Our blood contains special growth factors that stimulate the proliferation of fibroblasts and keratinocytes, which participate in the production of collagen and keratin, and play an important role in the turnover of damaged cells and the formation of new blood vessels, thus leading to the production of a new tissue.

The treatment is repeated 3-4 times over a 2-month period. After just one treatment, you can see up to 30% improvement. It is then recommended to repeat the treatment once a year or as needed.

Kristina Budin, Leg. nurse takes the blood before a skin rejuvenation treatment with PRF at LaDerma Clinic.

Contact the clinic for further advice or make an appointment for a consultation.


Etrebelle - Rejuvenation: wrinkles - La Derma
Reduction of wrinkles
Etrebelle - Large pores - La Derma
Large pores
Etrebelle - Volume restoration - La Derma
Etrebelle - Stretch marks - La Derma
Stretch marks
Hair - LaDerma
Decolletage - LaDerma
face, neck and décolletage

How the treatment works

Before the treatment, the practitioner will take 10 to 20 ml of your blood via a cannula. The pain you may feel is minimal, the same as in a classic blood test. Next, the practitioner will separate the plasma from other components of your blood using a high-speed centrifuge.

The treatment is carried out quickly and easily. PRF is applied under the skin using injections or microneedling, the method of application is determined by the practitioner. Results are visible a few days after treatment, while the full effect is expected in the coming months due to the process of creating new collagen and elastin. During this period, the skin is revitalized, becomes softer, more elastic and visibly regenerated.

Things to consider after treatment

After the procedure, it is possible to see redness, swelling and feel minimal pain in the treated area, which usually disappears within a few hours to 1 day, depending on the method of application. Most clients return to their normal activity immediately after treatment.

Within a few weeks of the treatment, a general improvement in the skin’s moisture, texture and tone can be seen. After three to six weeks, the development of new collagen and new blood vessels begins, and over the next three to six months, lines visibly disappear. The full effect of the treatment can take up to two years, depending on the person, but the results are long-lasting and worth waiting for.


PRF is a simple and safe treatment. Since PRF is extracted from your blood, there is no possibility of transmitting disease, triggering allergies or immunological reactions.

PRP therapy is not applied in platelet dysfunction, critical thrombocytopenia, hemodynamic instability, autoimmune diseases, acute and chronic diseases, pregnancy, chronic liver disease and anticoagulant therapy.

Combination with other treatments:
The treatment can be combined with e.g. fillers and thread lifts for an optimal facelift.